
Sodium taurolithocholate
CAS No. 6042-32-6
Sodium taurolithocholate ( —— )
产品货号. M19644 CAS No. 6042-32-6
主要人类代谢物,一种胆汁酸,可抑制放射性配体与毒蕈碱 M1 受体的结合,但不与 M2 或 M3 受体结合。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥316 | 有现货 |
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10MG | ¥381 | 有现货 |
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25MG | ¥591 | 有现货 |
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50MG | ¥786 | 有现货 |
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100MG | ¥1191 | 有现货 |
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200MG | ¥1766 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Sodium taurolithocholate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述主要人类代谢物,一种胆汁酸,可抑制放射性配体与毒蕈碱 M1 受体的结合,但不与 M2 或 M3 受体结合。
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产品描述The major human metabolite a bile acid which inhibits radioligand binding to muscarinic M1 but not to M2 or M3 receptors.
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体外实验Taurolithocholic acid (TLCA) at low concentrations (5 μM) tends to selectively increase the membrane-associated fraction of the e-isoform of PKC by 44.1% ± 40.2%.TLCA (10 μM) selectively induces translocation of theε-isoform of PKC to the hepatocellular membranes, a key step for activation of mobile PKC isoforms.
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体内实验Taurolithocholic acid (TLCA) exerts cholestatic effects via PI3K-dependent mechanisms in perfused rat Livers and rat hepatocyte couplets.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number6042-32-6
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分子量505.69
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分子式C26H44NNaO5S
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纯度>98% (HPLC)
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溶解度DMSO: 20 mg/mL
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SMILES[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ha C E Petersen C E Park D S et al. Investigations of the effects of ethanol on warfarin binding to human serum albumin[J]. 2000 7(2):114-121.